DATASHEET
Formulation
Yellow solid
Storage:
RT
Product Information:
Selective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50’s range from
40-90 nM). >300-fold selectivity for JNK as compared to related MAP kinases. Antiinflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable and active in vivo.
Description:
CAS Number: 129-56-6<br></br>Chemical Name: Anthra[1-9-cd]pyrazol-6(2H)-one<br></br>Molecular weight: 220.23<br></br>Formula: C14H8N2O<br></br>Solubility: DMSO (22 mg/ml) Ethanol (2 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by TLC NMR conforms