bs-82018C
[Life Science]
GW-5074
DATASHEET
Formulation Dark orange solid MP = 267-268°C
Storage: -20°C
Product Information:
Potent inhibitor of cRAF1 kinase (IC50 = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects In vivo via a mechanism that is independent of MEK, ERK, and Akt signaling. Cell permeable.
Description:
CAS Number: 220904-83-6<br></br>Chemical Name: 3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one<br></br>Molecular weight: 520.95<br></br>Formula: C15H8Br2INO2<br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: Dark orange solid MP = 267-268°C<br></br>Purity: 98% by TLC NMR conforms
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.