DATASHEET
Formulation
Orange solid
Storage:
-20°C
Product Information:
Potent selective inhibitor of VEGFR kinase (also known as Flk-1 and KDR). Inhibition of the activated kinase (IC50 = 0.4 µM) is 100-fold less than inhibition of the unactivated kinase (IC50 = 0.04 µM). Also inhibits PDGFR kinase (IC50 = 19.4 µM).
Description:
CAS Number: 5812-07-7<br></br>Chemical Name: 3-(4-Dimethylaminobenzylidene)-1,3-dihydroindol-2-one<br></br>Molecular weight: 264.33<br></br>Formula: C17H16N2O<br></br>Solubility: DMSO (25 mg/ml) <br></br>Physical Properties: Orange solid<br></br>Purity: 98% by TLC NMR conforms