bs-82012C
[Life Science]
BML-277
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
Potent selective inhibitor of Chk2 (IC50 = 15 nM). BML-277 has been screened against a panel of 35 kinases, and shows less that 25% inhibition of any other kinase at 10 µM, demonstrating the selectivity1. Also displays radioprotective activity, preventing apoptosis in human T-cells that were subjected to ionizing radiation (EC50 = 3.0 – 7.6 µM).
Description:
CAS Number: 516480-79-8<br></br>Chemical Name: 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide<br></br>Molecular weight: 363.81<br></br>Formula: C20H14ClN3O2<br></br>Solubility: DMSO (20 mg/ml); Ethanol (20 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC [50% ethyl acetate in hexanes; Rf = 0.17] NMR conforms
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.