bs-80508C
[Life Science]
Veliparib 2HCl (ABT-888)
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:317.2
Formula:C13H16N4O • 2HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in Water (up to 40 mg/ml).
Chemical Name:2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide, dihydrochloride
Formula:C13H16N4O • 2HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in Water (up to 40 mg/ml).
Chemical Name:2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide, dihydrochloride
Description:
PanPARP inhibitor (Ki = 5.2 PARP1 and 2.9 nM PARP2)1. Restores sensitivity to DNA alkylator/methylator temozolomide in glioma cells and xenografts2, and enhances radiotherapy sensitivity in endometrial carcinoma cells3. Also improves sensitivity to DNA replication inhibitor cisplatin in human oral carcinoma cells4.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.