DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:425.6
Formula:C27H39NO3
Purity:>98%
Solubility:Soluble in DMSO (up to 5 mg/ml), in DMF (up to 6 mg/ml), or in Ethanol (up to 20 mg/ml).
Chemical Name:(3β,23β)-17,23-Epoxy-3-hydroxyveratraman-11-one
Description:
Inhibitor of Hedgehog signaling (IC50 = 0.5-0.7 µM). Binds directly to Smoothened (Smo)1. Inhibits the response of target tissues to Sonic hedgehog signaling2. Induces COX-2 overexpression in human erythroleukemia cells3.