DATASHEET
Formulation
powder
Storage:
-20°C / protect from light
Product Information:
Molecular Weight:175.14
Formula:C6H9NO5
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Chemical Name:N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Description:
Inhibits PHD or prolyl hydroxylase domain-containing proteins, activating HIF1α1,2 and inhibiting JMJD2A (IC50 = 2.5 μM)3. Displays neuroprotective effects. Inhibits neuronal cell death caused by neurotrophin deprivation4. Prevents activation of the ATR/CHK1/p53 pathway and suppresses apoptosis induced by DNA damage5.