bs-80494C
[Life Science]
Leflunomide
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:270.21
Formula:C12H9F3N2O2
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 25 mg/ml).
Chemical Name:5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide
Formula:C12H9F3N2O2
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 25 mg/ml).
Chemical Name:5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide
Description:
A pyrimidine biosynthesis inhibitor DMARD (disease-modifying antirheumatic drug)1. Displays immunomodulatory activity inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH)2. Although the molecule directly responsible for DHODH is actually A77 1726, a metabolite of Leflunomide.
Rescues mice from acetaminophen-induced liver injury3.
Size: 50 mg, 250 mg50 mg, 250 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.