DATASHEET
Formulation
powder
Storage:
RT
Product Information:
Molecular Weight:403.53
Formula:C21H25NO CH4SO3
Purity:>98%
Solubility:Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 5 mg/ml with warming)
Chemical Name:3-(Endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane methanesulfonate
Description:
Centrally acting M1 muscarinic acetylcholine receptor antagonist (Ki=0.59 nM, rat).1 Also inhibits the dopamine transporter (Ki=160 nM).2 Enhances remyelination and significantly decreases clinical severity in the experimental autoimmune encephalomyelitis model of relapsing-remitting multiple sclerosis alone or in combination with immunosuppressive agents.3 Inhibits hepatitis C virus infection.4