DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:351.80
Formula:C17H18ClNO3S
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml).
Chemical Name:N-p-Tosyl-L-phenylalanine chloromethyl ketone
Description:
TPCK is an irreversible inhibitor of the serine protease chymotrypsin.1 It also inhibits certain cysteine proteases (bromelain, ficin, papain).1 TPCK inhibited (IC50 = 5 µM) the mitogen-induced activation of pp70s6k, a mitogen-regulated serine/threonine kinase involved in the G1 to S phase transition of the cell cycle.2