bs-80467C
[Life Science]
L-Cycloserine
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:102.1
Formula:C3H6N2O2
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml, warm) or in Water (up to 25 mg/ml).
Chemical Name:(S)-4-Amino-3-isoxazolidinone
Formula:C3H6N2O2
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml, warm) or in Water (up to 25 mg/ml).
Chemical Name:(S)-4-Amino-3-isoxazolidinone
Description:
Down-regulates sphingolipid biosynthesis via inhibition of serine palmitoyltransferase (3-ketodihydrosphingosine synthetase)1. The L isomer was shown to be 100-fold more potent than the D isomer at inhibition of the brain microsomal enzyme1. It is a useful pharmacological agent for lowering sphingolipid levels in cells2 as well as in animal models3. Inhibition of de novo ceramide biosynthesis with L-cycloserine positively affected the senescent phenotype, restoring neuronal signaling and reducing mitochondrial dysfunction in a cortical neuronal model of senescence4.
Size: 20 mg, 100 mg20 mg, 100 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.