DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:217.3
Formula:C9H15NO3S
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml) or in Water (up to 20 mg/ml).
Chemical Name:(2S)-1-(3-Mercapto-2-methyl-propionyl)-L-proline
Description:
Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 22 nM). Also inhibits the bifunctional Zn2+-containing leukotriene A4 hydrolase/aminopeptidase (LTA4 hydrolase) reversibly and competitively (Ki = 6.0 µM for leukotriene B4 formation and Ki = 60 nM for L-lysine-p-nitroanilide)2. Displays vasodilatory and antihypertensive effects in vivo. Clinically useful antihypertensive agent.