bs-80455C
[Life Science]
Tryptanthrin
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:248.24
Formula:C15H8N2O2
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml)
Chemical Name:Indolo(2,1-b)quinazoline-6,12-dione
Formula:C15H8N2O2
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml)
Chemical Name:Indolo(2,1-b)quinazoline-6,12-dione
Description:
A indoloquinazoline alkaloid found in various plant species and possessing intriguing pharmacological activities.1 Suppresses activation of BV2 microglia cells following LPS treatment and reduces production of proinflammatory cytokines via Nrf2, HO-1 and NFκB signaling.2 Displays antiinflammatory activity targeting IL-17.3 Inhibits indoleamine 2,3-dioxygenase 2 (IDO2) with an IC50 of 5-17 μM.4 Induces growth inhibition and neuronal differentiation in human neuroblastoma LA-N-1 cells.5
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.