DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:417.5
Formula:C16H23N3O4 • CH3SO3H
Purity:>98%
Solubility:Soluble in Water (up to at least 12 mg/ml)
Chemical Name:4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester, monomethanesulfonate
Description:
A serine protease inhibitor inhibiting plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancreatic fibrosis.1 Reduces weight gain and improves metabol-ism in obese rodent models.2 In clinical use (in Japan) for pancreatitis.3 Inhibits influenza virus replication in human tracheal epithelial cells.4 Reduces infection of Calu-3 lung cells by SARS-CoV-2 (responsible for COVID-19) via inhibition of the serine protease TMPRSS2 required for viral spike protein priming.5