DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:635.16
Formula:C32H43ClN2O9
Purity:>90%
Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 30 mg/ml with warming).
Chemical Name:
Description:
Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin1,2. Ansamitocin P3 is a maytansine analog which displays potent cytotoxicity against various human tumor cell lines2,3. Maytansine and its analogs cause extensive disassembly of microtubules and totally prevent tubulin spiralization4.