bs-80445C
[Life Science]
Gambogic acid
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:628.75
Formula:C38H44O8
Purity:>98%
Solubility:Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 50 mg/ml)
Chemical Name:
Formula:C38H44O8
Purity:>98%
Solubility:Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 50 mg/ml)
Chemical Name:
Description:
Induces apoptosis in a variety of cell lines acting as an antagonist of Bcl-2 family proteins (IC50 < 1 μM)1, however additional targets may contribute to its cytotoxicity. It suppresses cancer invasion and migration by inhibiting TGFβ1-induced epithelial-to-mesenchymal transition.2 Potentiates the chemosensitivity of cancer cells to other agents.3 Down-regulates surviving, reversing docetaxel resistance in cancer cells.4
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.