bs-80428C
[Life Science]
H89 · 2HCl
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:519.28
Formula:C20H20BrN3O2S·2HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml) or in Water (up to 10 mg/ml).
Chemical Name:N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride
Formula:C20H20BrN3O2S·2HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml) or in Water (up to 10 mg/ml).
Chemical Name:N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride
Description:
H-89 is a commonly used inhibitor of protein kinase A (PKA IC50 = 140 nM). Inhibits a variety of other kinases including S6K1 (IC50 = 80 nM), MSK1 (120 nM), ROCK II (270 nM), PKBα (2.6 µM), PKD, PRK2, RSK1 and 2, SGK, AMPK, CHK1 and MAPKAP-K1b (2.8 µM).1,2
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.