Molecular Weight:327.84 Formula:C14H17N3O2S · HCl Purity:>98% Solubility:Soluble in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml). Chemical Name:1-(5-Isoquinolinesulfonyl)homopiperazine HCl
Description:
Rho-associated kinase inhibitor (IC50 = 1.9 µM and 10.7 µM for Rho-associated kinase II and Rho-associated kinase respectively)1. Inhibits other kinases including cyclic nucleotide-dependent protein kinases.1 Reduces tryptamine-evoked vasopressor responses.2 attenuates bleomycin-induced pulmonary fibrosis in a mouse model.3 Clinically useful vasodilator.
Size:
50 mg, 250 mg50 mg, 250 mg
Applications:Life Science()
For research use only. Not intended for diagnostic or therapeutic use.