DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:269.30
Formula:C15H15N3O2
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml)
Chemical Name:4-(Acetylamino)-N-(2-aminophenyl)benzamide
Description:
Orally active histone deacetylase (HDAC) inhibitor, IC50 = 0.9, 0.9, 1.2 and >20 μM for HDAC1, HDAC2, HDAC3 and HDAC8 respectively.1 Mediates G1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo.2,3 Increases neuroplasticity during memory extinction.4 Protects beta cells from cytokine-induced apoptosis.4