DATASHEET
Formulation
powder
Storage:
RT
Product Information:
Molecular Weight:381.4
Formula:C17H14F3N3O2S
Purity:>98%
Solubility:Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).
Chemical Name:4-(5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
Description:
Selective inhibitor of cyclooxygenase-2 (COX-2) IC50 = 15 and 0.04 uM for COX-1 and COX-2 respectively1. Potent and clinically useful antiinflammatory agent2. Cancer chemopreventive agent3. May act synergistically with currently used anticancer agents4. Combination treatment with fasudil promotes recovery of injured spinal cord in rat models5. Cell permeable, active in vivo.