bs-80415C
[Life Science]
Bexarotene
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:348.49
Formula:C24H28O2
Purity:>98%
Solubility:Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 10 mg/ml with warming).
Chemical Name:4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
Formula:C24H28O2
Purity:>98%
Solubility:Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 10 mg/ml with warming).
Chemical Name:4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
Description:
A highly potent and selective retinoid X receptor (RXR) agonist (EC50=28, 25, 20 nM for RXRα, β, γ respectively)1. Clinically useful antineoplastic agent for cutaneous T-cell lymphoma2 Causes complete regression of mammary carcinoma3. Bexarotene significantly increases clearance of soluble β-amyloid in a mouse Alzheimer′s model and increases cognitive ability4. Reverses apoE4-driven brain pathology and behavioral deficits in vivo5.
Size: 10 mg, 100 mg10 mg, 100 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.