DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:Avg 840.0
Formula:C38H62N4O16 (tun. B)
Purity:>98%
Solubility:Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
Chemical Name:
Description:
Fermentation product from Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs varying in the number of carbon atoms in the fatty acid chain.
Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis1. Causes endoplasmic reticulum stress-induced autophagy2 and unfolded protein response3. Arrests cell cycle in late G14.