DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:1664.91
Formula:C72H85N19O18S5
Purity:>98%
Solubility:Soluble in DMSO (up to 15 mg/ml), or in Chloroform (up to 5 mg/ml).
Chemical Name:Fermentation product from Streptomyces azureus
Description:
Novel cyclopeptide antibiotic. Blocks bacterial protein synthesis by inhibition of mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery as well as the activity of initiation factor-1 (IF-2)1-2. Displays antitumor activity. Induces apoptosis and cell cycle arrest in various tumor cells via downregulation of FOXM1 expression3.