DATASHEET
Formulation
Lyophilized
Storage:
-20°C
Product Information:
Molecular Weight:805.00
Formula:C44H68O13
Purity:>98%
Solubility:Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml).
Chemical Name:Isolated from marine dionflagellates
Description:
A naturally occurring polyether marine toxin. Potent and selective inhibitor of protein phosphatases inhibiting PP2A completely at 1 nM and PP1 at higher concentrations, while PP2C is not inhibited. It is an extremely useful tool for studying cellular protein phosphorylation2. Induces apoptosis in a variety of cell types3. Activates atypical protein kinase isotypes and induces insulin-like effects in adipocytes4. Caution: SKIN IRRITANT, TUMOR PROMOTOR. Avoid contact.