DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:1085.15
Formula:C52H76O24
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).
Chemical Name:
Description:
Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL-induced apoptosis3.