bs-80399C [Life Science]
Mithramycin A
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Formulation powder

Storage: -20°C

Product Information:

Molecular Weight:1085.15

Formula:C52H76O24

Purity:>98%

Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).

Chemical Name:

Description:

Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL-induced apoptosis3.

Size: 1 mg, 5 mg 5 mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.