DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:495.5
Formula:C29H25N3O5
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml) or in DMF (up to 20 mg/ml).
Chemical Name:
Description:
Selective protein kinase G inhibitor (Ki =0.23, 4 and >10 μM for PKG, PKC and PKA respectively1. Arrests human skin fibroblast cell cycle after the G0/G1 boundary2. Abolishes the cGMP-induced relaxation in smooth muscle cells (IC50=60 nM)3. Cell permeable.