bs-80387C
[Life Science]
Cerulenin
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:223.27
Formula:C12H17NO3
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).
Chemical Name:2,3-Epoxy-4-oxo-7,10-dodecadienamide
Formula:C12H17NO3
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).
Chemical Name:2,3-Epoxy-4-oxo-7,10-dodecadienamide
Description:
Fatty acid synthase (FAS) inhibitor. Binds to β-keto-acyl-ACP synthase (KAS; IC50=1.5 μM), thus inhibiting protein acylation at concentrations of 45-134 μM1. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream of, both leptin and melanocortin receptors2. Reduces nutrient-induced insulin release from normal rat islets3. Induces apoptosis in human melanoma A-375 cells4.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.