DATASHEET
Formulation
powder
Storage:
RT
Product Information:
Molecular Weight:435.52
Formula:C24H29N5O3
Purity:>98%
Solubility:Soluble in DMSO (up to 40 mg/ml).
Chemical Name:(S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-pentanamido]butanoic acid
Description:
High affinity angiotensin AT1 receptor antagonist (Ki = 2.38 nM). Highly selective (30,000-fold) over AT2 receptors1,2. Normalizes the increased production of inflammatory cytokines in adipose and liver tissue in LPS-infused mice3. Clinically useful antihypertensive agent. Orally active.