bs-80379C
[Life Science]
Manidipine dihydrochloride
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:683.6
Formula:C35H38N4O6·2HCl
Purity:>98%
Solubility:Soluble in DMSO (up to at least 25 mg/ml)
Chemical Name:5-O-[2-(4-Benzhydrylpiperazin-1-yl)ethyl] 3-O-methyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochloride
Formula:C35H38N4O6·2HCl
Purity:>98%
Solubility:Soluble in DMSO (up to at least 25 mg/ml)
Chemical Name:5-O-[2-(4-Benzhydrylpiperazin-1-yl)ethyl] 3-O-methyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate dihydrochloride
Description:
Manidipine is a clinically useful antihypertensive.1,2 It is an inhibitor of L- and T-type calcium channels with high selectivity for vasculature. Manidipine has recently been found to be an inhibitor (IC50 = 4.8 µM) of the SARS-CoV-2 main protease, 3CLpro.3 It also acts as an early entry inhibitor of human cytomegalovirus (EC50 = 3.57 µM) via inhibition of the Immediate-Early 2 (IE2) protein.4
Size: 20 mg, 100 mg20 mg, 100 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.