DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:229.3
Formula:C8H11N3O3S
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml)
Chemical Name:4-Amino-1-[(2R,5S)-2-(hydroxymethyl)1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
Description:
A nucleoside analog reverse transcriptase inhibitor1. A potent and selective inhibitor of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2)2. Displays anti-inflammatory effects, including reduction of inflammasome-related proteins P2X7 and NLRP3, in retinal microvascular endothelial cells treated with high glucose and LPS as well as in streptozotocin diabetic mice3. Disrupts repeat element life cycle in colorectal cancer4.