bs-80366C
[Life Science]
2',3'-cGAMP
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:718.38
Formula:C20H22N10O13P2·2Na
Purity:>98%
Solubility:Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to 10 mg/ml)
Chemical Name:Adenylyl-(3’5’)-2’guanylic acid, cyclic nucleotide, disodium salt
Formula:C20H22N10O13P2·2Na
Purity:>98%
Solubility:Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to 10 mg/ml)
Chemical Name:Adenylyl-(3’5’)-2’guanylic acid, cyclic nucleotide, disodium salt
Description:
2',3'-cGAMP (CAS 1441190-66-4) is an endogenous STING (stimulator of interferon genes) agonist.1 Produced from ATP and GTP via the action of cGMP-AMP synthase (cGAS) which acts as a cytosolic DNA sensor.2,3 Induces autophagy which is a mechanism for clearance of DNA and viruses in the cytosol.4 DNA damage stimulates 2’,3’-cGAMP which stimulates an inflammatory response.5
Size: 1 mg,200 ug200 ug
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.