bs-80358C
[Life Science]
Fasnall HCl
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:374.93
Formula:C19H22N4S HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml) or in Water (up to 45 mg/ml)
Chemical Name:5,6-Dimethyl-N-[1-(phenylmethyl)-3-pyrrolidinyl]thieno[2,3-d]pyrimidin-4-amine benzenesulfonate hydrochloride
Formula:C19H22N4S HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml) or in Water (up to 45 mg/ml)
Chemical Name:5,6-Dimethyl-N-[1-(phenylmethyl)-3-pyrrolidinyl]thieno[2,3-d]pyrimidin-4-amine benzenesulfonate hydrochloride
Description:
A potent and selective fatty acid synthase (FASN) inhibitor acting via interfering with cofactor binding.1
IC50s = 147 and 213 nM respectively for inhibition of acetate and glucose incorporation into total lipids in HepG2 cells. IC50=5.84 μM in an isolated enzyme assay. Displays potent antitumor activity in the MMTV-Neu HER2+ breast cancer model1. Reduces HIV-1 virion production by 90% (EC50=213 nM).2
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.