DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:350.3
Formula:C13H15N3O2S • 2HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in water (up to 40 mg/ml)
Chemical Name:5-(1-Piperazinylsulfonyl)isoquinoline dihydrochloride
Description:
Inhibits the following kinases PKG (IC50=4 M), PKA (IC50=8 M), PKC (IC50=12 M)1. Increases human fibroblast reprogramming efficiency with PD0325901, CHIR99021, A83-01 and hLIF2. Improves single cell survival and supports high cloning efficiency in human pluripotent stem cells3.