bs-80339C
[Life Science]
NSC95397
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:310.39
Formula:C14H14O4S2
Purity:>98%
Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 1 mg/ml).
Chemical Name:2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone
Formula:C14H14O4S2
Purity:>98%
Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 1 mg/ml).
Chemical Name:2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone
Description:
A potent and selective inhibitor of Cdc25 phosphatase (Ki = 32, 96 and 40 nM for Cdc25A, B and C respectively). NSC-95397 inhibits the growth of several human tumor cell lines and blocks G2/M cell cycle transition.1 Induces cell cycle arrest, phosphorylation of EGFR and activation of ERK-1 and -2.2 Inhibits carboxyl-terminal binding protein a transcriptional corepressor that suppresses multiple pro-apoptotic and epithelial genes.3 Induces eryptosis in human erythrocytes.4
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.