bs-80338C
[Life Science]
Ro 31-8425
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:460.96
Formula:C26H24N4O2 · HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml)
Chemical Name:3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrol-2,5-dione hydrochloride
Formula:C26H24N4O2 · HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 10 mg/ml)
Chemical Name:3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrol-2,5-dione hydrochloride
Description:
Selective, reversible, ATP-competitive inhibitor of protein kinase C. Inhibits PKCα, β1, β2, γ and ε, IC50= 8, 8, 14,13 and 39 nM respectively.1 Extremely useful tool for probing PKC-dependent physiology2 or signaling pathways3. Increases MSC adhesion to an ICAM-1 coated substrate in vitro and enables targeted delivery of systematically administered MSCs to inflamed sites in vivo in a CD11a-dependent manner.4 Cell permeable.
Size: 1 mg, 5 mg 5 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.