bs-80329C
[Life Science]
BTB-1
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:297.7
Formula:C12H8ClNO4S
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml)
Chemical Name:4-Chloro-2-nitro-1-(phenylsulfonyl)-benzene
Formula:C12H8ClNO4S
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml)
Chemical Name:4-Chloro-2-nitro-1-(phenylsulfonyl)-benzene
Description:
A selective, ATP-competitive and reversible inhibitor of mitotic kinesin Kif18A, IC50=1.7 M1,2. Binds to an allosteric site near Kif18A loop 5 preventing a range of conformational changes thereby blocking motor function3. Inhibits the differentiation of mouse bone marrow cells to dendritic cells4. Suppresses the replication of influenza A virus, inhibiting activation of AKT, p38 MAPK, SAPK and RanBP3 leading to the prevention of nuclear export of viral ribonucleoprotein complexes. Greatly improves the viability of IAV-infected mice5.
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.