bs-80326C
[Life Science]
GAC Inhibitor 968
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:475.4
Formula:C27H27BrN2O
Purity:>98%
Solubility:Soluble in DMSO (up to (11 mg/ml); or ethanol (up to 1 mg/ml, warm)
Chemical Name:5-(3-bromo-4-(dimethylamino)phenyl)-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]-phenanthridin-4(1H)-one
Formula:C27H27BrN2O
Purity:>98%
Solubility:Soluble in DMSO (up to (11 mg/ml); or ethanol (up to 1 mg/ml, warm)
Chemical Name:5-(3-bromo-4-(dimethylamino)phenyl)-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]-phenanthridin-4(1H)-one
Description:
Allosteric inhibitor of glutaminase C (GAC)1. Inhibition of GAC blocks oncogenic transformation induced by Rho GTPases in fibroblasts and B lymphoma cells with no effect on normal cells2. Inhibits liver-type glutaminase GLS2 and suppresses breast tumor growth in vivo3,4. Reverses acquired erlotinib resistance in non-small cell lung cancer5.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.