DATASHEET
Formulation
powder
Storage:
RT
Product Information:
Molecular Weight:282.38
Formula:C18H22N2O
Purity:>98%
Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml)
Chemical Name:3,5-Di-tert-butyl-4-hydroxybenzylidene-malononitrile
Description:
Inhibits PDGF receptor tyrosine kinase (IC50 = 1.2 μM)1 and is a potent (10 nM) inhibitor of oxidative phosphorylation2. Inhibits cell growth by disrupting mitochondria3. Perturbs the golgi complex and blocks proliferation of vascular smooth muscle cells4.