DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:307.37
Formula:C16H18NO2S
Purity:>98%
Solubility:Soluble in DMSO (up to 80 mg/ml) or in Ethanol (up to 80 mg/ml).
Chemical Name:N-(4-Butylphenyl)-4-fluorobenzenesulfonamide
Description:
A GPR40 receptor antagonist1. Suppresses fatty acid-induced elevation of intracellular Ca++. Inhibits palmitic acid potentiated glucose–stimulated insulin secretion in Min6 pancreatic β cells in vitro. Lowers serum insulin levels, increases insulin sensitivity2 in obese Zucker rats (6 mg/kg)2. Reduces pancreatic β cell apoptosis in obese diabetic (db/db) rats3. Protects Min6 β cells from palmitic acid-induced ER stress and apoptosis4