DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:316.27
Formula:C12H25N3O2 2HCl
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml) or in Water (up to 30 mg/ml).
Chemical Name:(2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide, dihydrochloride
Description:
A nonpeptide neurotrophic factor receptor p75 (p75NTR) agonist which promotes survival signaling in neurotrophin-responsive cells.1 Promotes functional recovery in a mouse model of spinal contusion injury.2 Protects neurogenesis after traumatic brain injury.3 Reverses cholinergic neurite dystrophy in Alzheimer’s disease mouse models.4 Stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV-associated neuropathogenesis.5 Orally active and blood-brain barrier permeant.