bs-80312C
[Life Science]
Fascaplysin
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:306.75
Formula:C18H11ClN2O4
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml) or in Water (up to 2 mg/ml)
Chemical Name:12,13-Dihydro-13-oxopyrido[1,2-a:3,4-b’]diindol-5-ium chloride
Formula:C18H11ClN2O4
Purity:>98%
Solubility:Soluble in DMSO (up to 20 mg/ml) or in Water (up to 2 mg/ml)
Chemical Name:12,13-Dihydro-13-oxopyrido[1,2-a:3,4-b’]diindol-5-ium chloride
Description:
A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 μM) and is less selective for Cdk6/D1 (IC50 = 3.4 μM). Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3.
Size: 1 mg, 5 mg 5 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.