bs-80310C [Life Science]
PD-150606
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Formulation powder

Storage: -20°C

Product Information:

Molecular Weight:306.12

Formula:C9H7IO2S

Purity:>98%

Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml).

Chemical Name:(Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid

Description:

A selective, cell-permeable non-peptide calpain inhibitor (Ki for μ- and m-calpains = 0.21 and 0.37 μM respectively). Acts at the calcium binding site of calpain rather than the substrate-binding site. Inhibits calpain activity in two intact cell systems. Attenuates hypoxic/hypoglycemic injury to cerebrocortical neurons in culture and excitotoxic injury to Purkinje cells in cerebellar slices1. Displays cytoprotective effects in oxidant- and calcium ionophore-induced cell death2. Some protective effects may be due to inhibition of MMP activity3.

Size: 5 mg, 25 mg5 mg, 25 mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.