DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:269.23
Formula:C15H8N3O ∙ Na
Purity:>98%
Solubility:Soluble in DMSO (up to 15 mg/ml)
Chemical Name:11H-Indeno[1,2-b]quinoxaline-11-one oxime, sodium salt
Description:
JNK3 inhibitor (Kd = 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively). Displays anti-inflammatory and immunosuppresive activity. Inhibits LPS-induced proinflammatory cytokine and nitric oxide release in vitro.1 Attenuates collagen-induced arthritis severity and inhibits murine delayed-type hypersensitivity in vivo.2