bs-80306C
[Life Science]
STF-083010
DATASHEET
Formulation powder
Storage: RT
Product Information:
Molecular Weight:317.39
Formula:C15H11NO3S2
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml)
Chemical Name:N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamide
Formula:C15H11NO3S2
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml)
Chemical Name:N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamide
Description:
A novel small molecule inhibitor of IRE1. It inhibits IRE1 endonuclease activity but not its kinase activity after endoplasmic reticulum stress1-3. It displays significant antimyeloma activity in model human MM xenografts1. Induces apoptosis in pancreatic cancer cells and displays growth inhibition in a clonogenic growth assay in soft agar as well as in a xenograft in vivo model of pancreatic cancer4. Active in vivo.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.