bs-80304C
[Life Science]
HIF-2a-I2
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:308.65
Formula:C12H6ClFN4O3
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 35 mg/ml)
Chemical Name:N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
Formula:C12H6ClFN4O3
Purity:>98%
Solubility:Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 35 mg/ml)
Chemical Name:N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
Description:
Potent and selective HIF-2α inhibitor, Kd=81 nM.1 Binds to the HIF-2α PAS-B domain2 and interferes with Hif-2α / ARNT heterodimerization reducing target gene expression in a cellular model1. Highly selective for HIF-2α displaying a >60-fold selectivity over HIF-1α.1,2
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.