bs-80303C
[Life Science]
Pyocyanine
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:210.23
Formula:C13H10N2O
Purity:>98%
Solubility:Soluble in DMSO (up to 15 mg/ml).
Chemical Name:5-Methyl-1(5H)-phenazinone
Formula:C13H10N2O
Purity:>98%
Solubility:Soluble in DMSO (up to 15 mg/ml).
Chemical Name:5-Methyl-1(5H)-phenazinone
Description:
Pyocyanine, a redox-active phenazine produced by P. aeruginosa and other pathogens, is an electron receptor, which stimulates redox cycling in bacteria as well as in a variety of human cell lines. It enhances oxidative metabolism, which increases the formation of intracellular reactive oxygen species (ROS) via reduction of NADPH. Pyocyanine accelerates neutrophil apoptosis in vitro. Pyocyanine production by P. aeruginosa suppresses the acute inflammatory response by pathogen-driven acceleration of neutrophil apoptosis and associated reduction of local inflammation1,2.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.