DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:405.90
Formula:C22H16ClN3OS
Purity:>98%
Solubility:Soluble in DMSO (greater than 25 mg/ml)
Chemical Name:1-[(2-Chlorophenyl)methyl]-5'-phenyl-spiro[3H-indole-3,2'(3'H)-[1,3,4]thiadiazol]-2(1H)-one
Description:
CARP-1 functional mimetic. Interferes with CARP-1 binding to APC-2 (IC50=10-15 μM)1. Enhances CARP-1 expression and induces G2/M cell cycle arrest. Induces apoptosis and suppresses growth of medulloblastoma cells2 and malignant pleural mesothelioma cells3.