bs-80292C
[Life Science]
Indirubin-3'-monoxime
DATASHEET
Formulation powder
Storage: -20°C
Product Information:
Molecular Weight:277.29
Formula:C16H11N3O2
Purity:>98%
Solubility:Soluble in DMSO (up to 6 mg/ml) or in Ethanol (up to 4 mg/ml).
Chemical Name:3-[1,3-Dihydro-3-(hydroxyimino-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
Formula:C16H11N3O2
Purity:>98%
Solubility:Soluble in DMSO (up to 6 mg/ml) or in Ethanol (up to 4 mg/ml).
Chemical Name:3-[1,3-Dihydro-3-(hydroxyimino-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
Description:
A potent GSK-3β inhibitor (IC50=22 nM)1. Also inhibits CDK1 (IC50=180 nM) and CDK5 (IC50=100 nM)1. Displays antimitotic properties and induces endoreplication following prophase arrest in HBL-100 cells2. Possesses antiangiogenic activity3. Attenuates β-amyloid-associated neuropathology in a mouse model of Alzheimer’s disease4. Cell permeable.
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.