DATASHEET
Formulation
powder
Storage:
-20°C
Product Information:
Molecular Weight:229.24
Formula:C12H11N3O2
Purity:>98%
Solubility:Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
Chemical Name:2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quainazolinone
Description:
Potent and selective adenylyl cyclase inhibitor. Selective for AC5 over AC3 and AC2 (IC50 = 8.3 μM, 132 μM and 1.7 mM respectively)1,2. More recently shown to indiscriminately inhibit AC63. An extremely useful tool for probing the involvement of adenylyl cyclases in cellular signaling4.