DATASHEET
Formulation
oil
Storage:
-20°C
Product Information:
Molecular Weight:439.63
Formula:C28H41NO3
Purity:>98%
Solubility:Soluble in DMSO (up to 50 mg/ml)
Chemical Name:N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)dopamine
Description:
Endogenous conjugate of arachidonic acid and dopamine.1 May be the “endogenous capsaicin like substance” in the CNS acting at TRPV1 channels, EC50~ 50 nM1. Also acts as a selective cannabinoid CB1 agonist (Ki=0.25 and 15 M for CB1 and CB2 respectively)2 and results in a distinct signaling profile from any known cannabinoid3. Competitive inhibitor of FAAH and anadamide transport.4. Modulates acute systemic inflammation via non-hematopoietic TRPV1.5